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  Indian J Med Microbiol
 

Figure 2: Effects of Aloperine on PDGF-BB-induced cell cycle progression. HPASMCs were treated with 20 ng/ml PDGF-BB for 24 h in the absence or presence of Aloperine (0.5 mM). Quantification of HPASMCs in the G0/G1, S and G2/M phases was determined using flow cytometric evaluation. Values are expressed as the mean ± standard deviation. ##P < 0.01 versus the control group; **P < 0.01 versus PDGF-BB treated cells (n = 6). (a): Control group; (b): PDGF-BB group; (c): PDGF-BB + Aloperine. PDGF: Platelet-derived growth factor, HPASMCs: Human pulmonary artery smooth muscle cells

Figure 2: Effects of Aloperine on PDGF-BB-induced cell cycle progression. HPASMCs were treated with 20 ng/ml PDGF-BB for 24 h in the absence or presence of Aloperine (0.5 mM). Quantification of HPASMCs in the G<sub>0</sub>/G<sub>1</sub>, S and G<sub>2</sub>/M phases was determined using flow cytometric evaluation. Values are expressed as the mean ± standard deviation. <sup>##</sup><i>P</i> < 0.01 versus the control group; **<i>P</i> < 0.01 versus PDGF-BB treated cells (<i>n</i> = 6). (a): Control group; (b): PDGF-BB group; (c): PDGF-BB + Aloperine. PDGF: Platelet-derived growth factor, HPASMCs: Human pulmonary artery smooth muscle cells