Chinese Journal of Physiology

REVIEW ARTICLE
Year
: 2020  |  Volume : 63  |  Issue : 6  |  Page : 245--249

Interplay of COVID-19 and physiological dysfunctions


Yu-Hsiu Chang1, Chih-Heng Huang1, Po-Shiuan Hsieh2 
1 Institute of Preventive Medicine, National Defense Medical Center, New Taipei City, Taiwan
2 Department of Physiology and Biophysics, National Defense Medical Center; Department of Medical Research, Tri-Service General Hospital, Taipei, Taiwan

Correspondence Address:
Prof. Po-Shiuan Hsieh
Department of Physiology and Biophysics, National Defense Medical Center, No. 161, Section 6, Min-Chuan East Road, Taipei 114
Taiwan

The outbreak of the global coronavirus disease 2019 (COVID-19) pandemic continues to impact the socioeconomic fabric and the general well-being of numerous populations and communities around the world. As cases continue to rise exponentially, gaining a better understanding of the pathophysiology and the associated clinical implications of SARS-CoV-2, the causative agent of COVID-19, becomes increasingly necessary. In this article, we delineate the role of COVID-19 in physiological and immunological dysfunction. Specifically, we highlight the various possible mechanisms and effects of SARS-CoV-2 infections on major organ systems as well as their contribution toward multiorgan system failure. By analyzing studies and statistics regarding various comorbidities in COVID-19 patients, we make inferences on the linkage between COVID-19, immune injury, multiorgan system damage, and disease progression.


How to cite this article:
Chang YH, Huang CH, Hsieh PS. Interplay of COVID-19 and physiological dysfunctions.Chin J Physiol 2020;63:245-249


How to cite this URL:
Chang YH, Huang CH, Hsieh PS. Interplay of COVID-19 and physiological dysfunctions. Chin J Physiol [serial online] 2020 [cited 2021 Jan 17 ];63:245-249
Available from: https://www.cjphysiology.org/article.asp?issn=0304-4920;year=2020;volume=63;issue=6;spage=245;epage=249;aulast=Chang;type=0