Figure 8: Schematic representation of the inhibition effects of resveratrol on obesity and aging sarcopenia. The mechanisms underlying the pathophysiology of sarcopenic obesity. In obesity skeletal muscle, adipocytes undergo hypertrophy activation resulting in skeletal muscle atrophy due to accumulation of pro-inflammation as well as mitochondrial dysfunction together with senescent muscle cells. Skeletal muscle inflammation triggers and supports sarcopenic obesity development. ECM: Extracellular matrix, ANP: Atrial natriuretic peptide, BNP: Brain natriuretic peptide, MMP: Matrix metalloproteinases, PI3K: Phosphatidylinositol 3 kinase, UPA: Urokinase-type plasminogen activator, FGF: Fibroblast growth factor.