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  Indian J Med Microbiol
 

Figure 5: Suppressive effects of A784168 on Ca2+ signals triggered by high Ca2+, cinacalcet, and spermine. [Ca2+]i was measured in bEND.3 cells bathed in Ca2+-containing solution; cells were pretreated with or without 1 μM A784168 for 8 min and then treated with (a) 3 mM Ca2+; significant (*P < 0.05) differences between the control and A784168 group began after 187 s; (b) 10 μM cinacalcet; significant (*P < 0.05) differences between the control and A784168 group began after 114 s; or (c) 3 mM spermine; significant (*P < 0.05) differences between the control and A784168 group began after 192 s. Results are mean ± SEM, with each group having 25–37 cells obtained from three to four separate experiments.

Figure 5: Suppressive effects of A784168 on Ca<sup>2+</sup> signals triggered by high Ca<sup>2+</sup>, cinacalcet, and spermine. [Ca<sup>2+</sup>]i was measured in bEND.3 cells bathed in Ca<sup>2+</sup>-containing solution; cells were pretreated with or without 1 μM A784168 for 8 min and then treated with (a) 3 mM Ca<sup>2+</sup>; significant (*<i>P</i> < 0.05) differences between the control and A784168 group began after 187 s; (b) 10 μM cinacalcet; significant (*<i>P</i> < 0.05) differences between the control and A784168 group began after 114 s; or (c) 3 mM spermine; significant (*<i>P</i> < 0.05) differences between the control and A784168 group began after 192 s. Results are mean ± SEM, with each group having 25–37 cells obtained from three to four separate experiments.